This study reports on a strain-sensitivegranular adhesive inspired by the core–shell architectures of natural basil seeds for iHMI as well as human–metaverse interfacing. The granularadhesive sensor consists of easily fragmented hydropellets as a core andtissue-adhesive catecholamine layers as a shell, satisfying great on-skininjectability, ionic-electrical conductivity, and sensitive resistance changes through reversible yet robust cohesion among the hydropellets.